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Inspired by the real-life story of Audrey Santo, who died at age 23 in 2007 after she was left in a vegetative state since childhood, the film centers on a Vatican-ordered investigation into reported miracles surrounding the teenage girl with akinetic mutism.
| Name | Character | Team | |
|---|---|---|---|
| Mabel Byrne | Jessica 'JeeJee' Santo | Unowned | |
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Emily VanCamp | Myriam Levy | Unowned |
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Jennifer Esposito | Linda Santo | Unowned |
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Aidan Quinn | Bishop Ryan | Unowned |
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Joshua Bowman | Frank Belanger | Unowned |
| Ciaran Byrne | Fr. Luke McAteer | Unowned | |
| Robert Wahlberg | Dr. Sam Bernard | Unowned | |
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Jeff Wiens | Dr. Tony Messina | Unowned |
| David Chiavaroli | James Santo Jr. | Unowned | |
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Jessica Galinas | Natalie Comeau | Unowned |
| Heather Benson | Pilgrim | Unowned |