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Sis is the maid in the Higgins home, adjoining that of Prof. Doolittle, a physical culture specialist. Sis takes up the study of "fysical culture" with disastrous results, for her throwing out of the medicine ball renders the Doolittle maid a subject for hospital treatment. Sis is then loaned to the Professor's establishment.
| Name | Character | Team | |
|---|---|---|---|
| Rose Melville | Sis Hopkins | Unowned | |
| Henry Murdock | Professor Doolittle | Unowned | |
| Olive West | The Professor's Sister | Unowned | |
| C.D. Peruchi | Skull N. Bones | Unowned | |
| Richard Purdon | Mr. Higgins | Unowned | |
| Frances Ne Moyer | The Maid | Unowned |